Choose the correct signal transduction pathway GATE Biotechnology

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Choose the correct signal transduction pathway GATE-Biotechnology

(A) Hormone 7 TM receptor Gprotein cAMP PKA → → → →
(B) Hormone Gprotein 7 TM receptor cAMP PKA → → → →
(C) Hormone 7 TM receptor Gprotein PKA cAMP → → → →
(D) Hormone 7 TM receptor cAMP G protein PKA


By:tarun101

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A:Hormone 7 TM receptor Gprotein cAMP PKA → → → →
Explanation: In the G protein associated signal cascade system, binding of hormone to
a cell surface receptor, like the 7TM (a 7 transmembrane alpha helices) which is a
part of G protein. This will activate production of second messengers like cAMP by
the enzyme adenylate cyclase. The cAMP in turn binds and activates down stream
signal proteins line cAMP dependent protein kinase A (PKA). 

13priya

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